Anomalous Celiac Trunk Variation Encountered in Y-90 Radioembolization

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Anomalous branching pattern of celiac trunk

The hepatic, splenic and left gastric arteries are considered as the ‘‘main classic branches’’ of the celiac trunk (CT). In the embryonic life, yolk sac is supplied by vitelline arteries. Later they gradually fuse and help in formation of the arteries dorsal to the mesentery of the gut. In the adult, they are developed as CT, superior mesenteric and inferior mesenteric arteries. These vessels s...

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Radioembolization offers a novel way to treat the nonresectable, liver predominant hepatic malignancies with better tumor response and overall progression-free survival rates. Transarterial catheter-based radioembolization procedure involves the hepatic arterial administration of glass- or resin-based beta emitting Yttirum-90 microspheres. Safe delivery of the tumoricidal radiation dose require...

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Phantom validation of quantitative Y-90 PET/CT-based dosimetry in liver radioembolization

BACKGROUND PET/CT has recently been shown to be a viable alternative to traditional post-infusion imaging methods providing good quality images of 90Y-laden microspheres after selective internal radiation therapy (SIRT). In the present paper, first we assessed the quantitative accuracy of 90Y-PET using an anthropomorphic phantom provided with lungs, liver, spine, and a cylindrical homemade lesi...

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Side Effects of Yttrium-90 Radioembolization

Limited therapeutic options are available for hepatic malignancies. Image guided targeted therapies have established their role in management of primary and secondary hepatic malignancies. Radioembolization with yttrium-90 ((90)Y) microspheres is safe and efficacious for treatment of hepatic malignancies. The tumoricidal effect of radioembolization is predominantly due to radioactivity and not ...

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PURPOSE Selective Internal Radiation Therapy (SIRT) with 90yttrium (Y-90) is an increasingly used therapeutic option for unresectable liver malignancies. Nontarget embolization of extrahepatic tissue secondary to vascular shunting can lead to SIRT associated complications. Our aim was to assess whether extrahepatic shunts can reliably be diagnosed based on hepatic digital subtraction angiograph...

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ژورنال

عنوان ژورنال: Proceedings of IMPRS

سال: 2020

ISSN: 2641-2470

DOI: 10.18060/24637